Wholesale noun the sale of goods in quantity, as to retailers or jobbers, for resale(opposed to retail ). adjective 2. of, relating to, or engaged in sale by wholesale. 3. extensive; broadly indiscriminate: wholesale discharge of workers. adverb 4. in a wholesale way; on wholesale terms: I can get it for you wholesale. 5. in large quantities; on a large scale, especially without discrimination: Wild horses were slaughtered wholesale. verb (used with or without object), wholesaled, wholesaling. 6. to sell by wholesale.